Magnesium's Role in

"Neuronal Excitability"

Magnesium acts as a natural calcium channel blocker and plays a crucial role in maintaining neuronal stability. Mg²⁺ modulates the activity of NMDA receptors (which are involved in excitatory neurotransmission) and stabilizes the resting membrane potential. Mg²⁺ deficiency can lead to increased calcium influx through NMDA receptors, enhancing neuronal excitability. This can result in symptoms such as muscle twitching, cramps, and even convulsions, as the neurons become more prone to spontaneous firing.

Pumpkin Seeds

Nuts & seeds are on the "Good" list in the Parkinson PRO, Mediterranean, and MIND diets.

Dark Chocolate

If you need an excuse to include this fabulous "fruit" in your diet, here is it: Dark chocolate is a rich source of magnesium.

Spinach

As if we need more reasons to load up on leafy greens, spinach is one of the foods with the highest magnesium concentrations.

About the Instructor

Laurie Mischley, ND PhD MPH studied naturopathic medicine (ND) at Bastyr University and epidemiology (MPH) and nutritional sciences (PhD) at the University of Washington and she maintains appointments at both Universities.

Her work is focused on identifying the nutritional requirements unique to individuals with Parkinson’s Disease (PD); she has published on coenzyme Q10, lithium, NAD+, and glutathione deficiency (www.lauriemischley.com).

She is Principal Investigator of the Modifiable Variables in Parkinsonism (MVP) Study (MVP-study.com), which is attempting to describe why some people with PD progress slower than others.

She is working on ways to study, package and deliver evidence-based lifestyle modification as a therapeutic strategy. She founded the Parkinson Center for Pragmatic Research (www.parkinson-cpr.com) and the canine scent-based PD screening tool, ParK-9 (www.Park-9.com), developed a patient-reported outcome measure to assess PD severity (www.PD-symptoms.com), and built the Parkinson Symptom Tracking (PRO-PD) App.

Curriculum

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